Virulence Factors |
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| This is a list of virulence factors compiled for the reference genome of Clostridium perfringens: C. perfringens ATCC 13124 and C. perfringens SM101. The column headers list the name of the virulence factor, the gene symbol for that virulence factor, the locus of that protein as identified on pathema and the name of the protein (as annotated on pathema based on the evidence). There is also a link to the reference if available. This list is a work in progress and will be updated as new results are available. |
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| Organism |
Virulence factors |
Gene symbol |
Locus |
Protein name |
PMID |
| Clostridium perfringens ATCC 13124 |
Fibronectin-binding protein |
fbpA |
CPF_2101 |
fibronectin-binding protein |
14523111 |
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GroEL |
groL |
CPF_2573 |
chaperonin, GroL |
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VirR/VirS two component system |
virS |
CPF_1751 |
sensor histidine kinase VirS |
8052128 |
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Alpha-clostripain |
cloSI |
CPF_0840 |
clostripain |
8341259 |
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Alpha-toxin |
plc |
CPF_0042 |
phospholipase C |
16887662 |
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Enterotoxin |
entA |
CPF_1467 |
SH3 domain protein |
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entC |
CPF_0454 |
SH3 domain protein |
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entD |
CPF_0587 |
N-acetylmuramoyl-L-alanine amidase/SH3 domain protein |
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entB |
CPF_1562 |
SH3 domain/NlpC/P60 family protein |
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Hemolysin |
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CPF_0439 |
CBS/transporter associated domain protein |
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CPF_1725 |
hemolysin III |
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CPF_2072 |
hemolysin A |
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hlyIII |
CPF_2171 |
hemolysin III |
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Kappa-toxin (collagenase) |
colA |
CPF_0166 |
microbial collagenase |
8282691 |
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Mu-toxin (neuraminidase) |
nagH |
CPF_0184 |
hyaluronoglucosaminidase |
8177218 |
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nagI |
CPF_0875 |
putative O-GlcNAcase nagJ |
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nagJ |
CPF_1442 |
O-GlcNAcase nagJ |
16541109 |
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nagK |
CPF_1487 |
putative hyaluronoglucosaminidase |
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nagL |
None Found |
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Perfringolysin O (theta-toxin/PFO) |
pfoA |
CPF_0156 |
perfringolysin O |
16926413 |
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Sialidase |
nanH |
CPF_0985 |
sialidase |
2901987 |
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nanI |
CPF_0721 |
sialidase |
2034213, 18218621 |
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nanJ |
CPF_0532 |
sialidase |
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| Clostridium perfringens SM101 |
Fibronectin-binding protein |
fbpA |
CPR_1815 |
fibronectin-binding protein |
14523111 |
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GroEL |
groL |
CPR_2275 |
chaperonin, GroL |
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VirR/VirS two component system |
virS |
CPR_1481 |
sensor histidine kinase VirS |
8052128 |
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virR |
CPR_1482 |
DNA-binding response regulator VirR |
8052128 |
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Alpha-clostripain |
cloSI |
CPR_0833 |
clostripain |
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Alpha-toxin |
plc |
CPR_0041 |
phospholipase C |
16887662 |
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Enterotoxin |
entA |
CPR_1266 |
SH3 domain protein |
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entC |
None Found |
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entD |
None Found |
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entB |
CPR_1353 |
SH3 domain/NlpC/P60 family protein |
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Hemolysin |
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CPR_0433 |
CBS/transporter associated domain protein |
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CPR_1453 |
hemolysin III |
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CPR_1786 |
hemolysin A |
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hlyIII |
CPR_1882 |
hemolysin III |
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Kappa-toxin (collagenase) |
colA |
CPR_0162 |
microbial collagenase |
8282691
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Mu-toxin (neuraminidase) |
nagH |
CPR_0181 |
hyaluronoglucosaminidase, degenerate |
8177218
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nagI |
None Found |
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nagJ |
CPR_1248 |
O-GlcNAcase nagJ, degenerate |
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nagK |
None Found |
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nagL |
None Found |
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Perfringolysin O (theta-toxin/PFO) |
pfoA |
None Found |
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Sialidase |
nanH |
CPR_0877 |
sialidase |
2901987
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nanI |
None Found |
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nanJ |
None Found |
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